Weaver arrived at County General as Chief Resident and later became an attending physician, then rose to Chief of Emergency Medicine and finally Hospital Chief of Staff. Through it all, Weaver remained unfazed by her physical disability, which required her to move about the crowded and chaotic ER with a crutch, and by her controversial standing among colleagues, several of whom regard her as abrasive, cold and officious. Having had some heterosexual relationships, Weaver is eventually revealed as lesbian, her sexual orientation being a key point in some of the episodes, particularly when she fights in court to keep her son, Henry.